Weekly Changes in the Clozapine Concentration-to-Dose Ratio During Clozapine Titration in Japanese Patients With Schizophrenia
Measuring clozapine blood levels early in the titration phase helps estimate the metabolic capacity of patients. Furthermore, it is essential to pay attention to inflammation, which may increase clozapine C/D ratios.
Authors
- Mutsumi Sakata
- Naoki Horikawa (ORCID: https://orcid.org/0000-0001-8480-6420)
- Daisuke Kume (ORCID: https://orcid.org/0000-0003-4461-930X)
- Kazuro Ikawa (ORCID: https://orcid.org/0000-0002-9349-4067)
- Hiroaki Tomita (ORCID: https://orcid.org/0000-0003-2628-880X)
- Yuki Kikuchi (ORCID: https://orcid.org/0000-0002-1184-8918)
- Hiroshi Komatsu (ORCID: https://orcid.org/0000-0002-7602-0281)
Institutions
- Hiroshima University (JP)
- Tohoku University (JP)
- Tohoku University Hospital (JP)
- Miyagi Prefecture Ishinomaki Technical High School (JP)
Publication Details
- Journal
- Journal of Clinical Psychopharmacology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1097/jcp.0000000000002003
- Citations
- 5
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 7.36