hnRNPA2B1 facilitates ovarian carcinoma metastasis by sorting cargoes into small extracellular vesicles driving myofibroblasts activation
These findings highlight the miRNA sorting to sEVs mediated by hnRNPA2B1 as an important mechanism involved in OvCa metastasis, which may illuminate new therapeutic strategies.
Authors
- Jingni Zhang (ORCID: https://orcid.org/0000-0003-4675-7853)
- Wenhan Li (ORCID: https://orcid.org/0000-0002-9412-1166)
- Qiulei Wu (ORCID: https://orcid.org/0000-0002-6232-9528)
- Feiquan Ying (ORCID: https://orcid.org/0000-0003-2697-3604)
- Jing Cai (ORCID: https://orcid.org/0000-0002-0302-9998)
- Lili Yu (ORCID: https://orcid.org/0000-0002-4625-3957)
- Lanqing Gong (ORCID: https://orcid.org/0000-0003-4183-9710)
- Pan Liu (ORCID: https://orcid.org/0000-0002-3066-652X)
- Guoqing Li (ORCID: https://orcid.org/0000-0002-6557-1301)
- Zehua Wang (ORCID: https://orcid.org/0000-0001-6423-8219)
- Xiaoqing Yi (ORCID: https://orcid.org/0000-0002-4931-900X)
- Lin Huang (ORCID: https://orcid.org/0009-0006-7948-1995)
- Rui Gao
- Linjuan Xu
- Xiaoli Liu (ORCID: https://orcid.org/0009-0006-0634-2652)
Institutions
- Union Hospital (HK)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1186/s12951-025-03342-w
- Citations
- 3
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province