KIF14 plays a role in the regulation of the cell cycle and has implications for prognosis in clear cell renal cell carcinoma
KIF14 down-regulates cell cycle proteins CyclinD1 and CDK4 to facilitate the proliferation of ccRCC cells, suggesting its potential as a therapeutic target and prognostic biomarker in ccRCC.
Authors
- Xin Lai (ORCID: https://orcid.org/0000-0003-4913-5822)
- Siren Feng
- Jie Wang (ORCID: https://orcid.org/0000-0002-5852-9754)
- Zhijun Sun (ORCID: https://orcid.org/0000-0003-2962-5488)
- Hu Zhao (ORCID: https://orcid.org/0000-0001-7796-6944)
- Li Bi (ORCID: https://orcid.org/0000-0002-9695-5084)
Institutions
- Ningbo No. 2 Hospital (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- BMC Urology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1186/s12894-025-01732-8
- Citations
- 6
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 9.11
Funders
- Medical Science and Technology Project of Zhejiang Province
- Science and Technology Program of Zhejiang Province