Platycodon grandiflorum exosome-like nanoparticles: the material basis of fresh platycodon grandiflorum optimality and its mechanism in regulating acute lung injury
Fresh PG has better anti-inflammatory and repair effects than its dried form. As one of the most effective active substances in fresh PG, PGLNs may regulate macrophage inflammation and polarization by regulating metabolic pathways including lipid metabolism and glycolysis, so as to reduce inflammation and repair lung injury.
Authors
- Fangguo Lu (ORCID: https://orcid.org/0000-0002-8256-9932)
- Yi Ning (ORCID: https://orcid.org/0000-0002-7737-580X)
- Kangyu Wang
- Zhuolin Liu (ORCID: https://orcid.org/0000-0001-8019-2054)
- Jingmin Fu
- Jiaxin Yang (ORCID: https://orcid.org/0000-0002-7925-6935)
- Ling Li (ORCID: https://orcid.org/0000-0001-6485-9621)
- Zhiying Feng
- Xue‐Lian Jiang (ORCID: https://orcid.org/0000-0002-7215-3378)
- Jiawang Huang
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1186/s12951-025-03331-z
- Citations
- 25
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 20.15
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province