A 0.05 mm3 diode-based single charged-particle real-time radiation detector for electron radiotherapy
Real-time radiation monitoring at the single-particle level is an unmet need for electron radiotherapy, especially for dose deposition to targets in motion or critical OARs. We have developed a first-in-class CMOS-based 0.05 mm<sup>3</sup> single electron sensitive detector. The chiplet integrates all the requisite electronics. The functionality of the system is verified under 6 and 9 MeV clinical electron beams. Percentage depth vs. pulse-width curves for 6 and 9 MeV beams are measured and verified using Monte-Carlo simulations. The proposed system has the potential to enhance the electron radiotherapy quality and safety, providing real-time dosimetry from multiple sites simultaneously.
Authors
- Michel M. Maharbiz (ORCID: https://orcid.org/0000-0002-8577-4894)
- Rahul Lall
- Kyoungtae Lee (ORCID: https://orcid.org/0000-0002-4605-1415)
- Mekhail Anwar (ORCID: https://orcid.org/0000-0002-6650-2594)
Institutions
- University of California, San Francisco (US)
- Daegu Gyeongbuk Institute of Science and Technology (KR)
- University of California, Berkeley (US)
Publication Details
- Journal
- Physics and Imaging in Radiation Oncology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1016/j.phro.2025.100762
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.00