Development and validation of a framework for registration of whole-mount radical prostatectomy histopathology with three-dimensional transrectal ultrasound
The framework proposed in this study accomplishes precise registration between prostate pathology and imaging. The methodologies employed hold the potential for broader application across diverse imaging modalities and other target organs. However, limitations such a small sample size and the need for manual segmentation should be considered when interpreting te results. Future efforts should focus on automating key steps to enhance reproducibility and scalability.
Authors
- Jorg R. Oddens (ORCID: https://orcid.org/0000-0002-6079-5613)
- Marije J. Zwart
- Massimo Mischi (ORCID: https://orcid.org/0000-0002-1179-5385)
- Arnoud W. Postema (ORCID: https://orcid.org/0000-0003-0629-871X)
- Wim Zwart
- Auke Jager (ORCID: https://orcid.org/0000-0003-3937-7262)
- Harrie P. Beerlage (ORCID: https://orcid.org/0000-0001-8422-2441)
- Daniël L. van den Kroonenberg (ORCID: https://orcid.org/0000-0001-8448-4193)
Institutions
- Leiden University Medical Center (NL)
- Angiogenesis Foundation (US)
- Amsterdam Neuroscience (NL)
- Eindhoven University of Technology (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- BMC Urology
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1186/s12894-025-01736-4
- Citations
- 3
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- European Commission