Chromosome 1p Loss and 1q Gain for Grading of Meningioma
These findings highlight a role for cytogenetic profiling in the next iteration of CNS WHO grading, with a specific focus on chromosome 1p loss and 1q gain, suggesting that chromosome 1p loss, in addition to 22q loss, should be added as a criterion for a CNS WHO grade of 2 and addition of 1q gain as a criterion for a CNS WHO grade of 3.
Authors
- Jennifer Moliterno (ORCID: https://orcid.org/0000-0002-6413-5874)
- Jeff Liu (ORCID: https://orcid.org/0000-0002-9928-7552)
- Farshad Nassiri (ORCID: https://orcid.org/0000-0002-0797-3425)
- Aaron Cohen‐Gadol (ORCID: https://orcid.org/0000-0002-4946-1524)
- Murat Günel (ORCID: https://orcid.org/0000-0002-2290-7055)
- Marcos Tatagiba
- Jelle Wesseling (ORCID: https://orcid.org/0000-0002-8940-2676)
- Felix Behling (ORCID: https://orcid.org/0000-0002-1083-1276)
- Chloe Gui (ORCID: https://orcid.org/0000-0002-6685-1970)
- Silky Chotai (ORCID: https://orcid.org/0000-0001-5981-3231)
- David Capper (ORCID: https://orcid.org/0000-0003-1945-497X)
- Olivia Singh (ORCID: https://orcid.org/0000-0001-7321-6775)
- Leeor Yefet
- Stephen Yip (ORCID: https://orcid.org/0000-0002-8514-9861)
- Derek S. Tsang (ORCID: https://orcid.org/0000-0002-9762-6901)
- Jill S. Barnholtz‐Sloan (ORCID: https://orcid.org/0000-0001-6190-9304)
- Alireza Mansouri (ORCID: https://orcid.org/0000-0002-7442-7539)
- Serge Makarenko (ORCID: https://orcid.org/0000-0002-6283-249X)
- Andrew Ajisebutu
- Justin Z. Wang (ORCID: https://orcid.org/0000-0001-8998-7443)
- Kenneth Aldape (ORCID: https://orcid.org/0000-0001-5119-7550)
- Felix Sahm (ORCID: https://orcid.org/0000-0001-5441-1962)
- Yosef Ellenbogen (ORCID: https://orcid.org/0000-0003-1390-1361)
- Gelareh Mohammed Zadeh (ORCID: https://orcid.org/0000-0002-6637-4502)
- Felix Ehret (ORCID: https://orcid.org/0000-0001-6177-1755)
- Qingxia Wei (ORCID: https://orcid.org/0000-0002-7723-6180)
- Julio Sosa (ORCID: https://orcid.org/0000-0001-5516-5724)
- Vikas Patil (ORCID: https://orcid.org/0000-0002-7997-7759)
- Lola B. Chambless (ORCID: https://orcid.org/0000-0001-5864-5387)
- Andrew E. Sloan (ORCID: https://orcid.org/0000-0001-9607-5063)
- Sheila Mansouri (ORCID: https://orcid.org/0000-0002-7255-207X)
- Ghazaleh Tabatabai (ORCID: https://orcid.org/0000-0002-3542-8782)
- Andrew Gao (ORCID: https://orcid.org/0000-0002-2204-3277)
- Alexander Landry (ORCID: https://orcid.org/0000-0002-7250-8466)
Institutions
- University of Southern California (US)
- University Health Network (CA)
- University of British Columbia (CA)
- University of Toronto (CA)
- Heidelberg University (DE)
- Princess Margaret Cancer Centre (CA)
- Yale University (US)
- Humboldt-Universität zu Berlin (DE)
- Princess Máxima Center (NL)
- Bernstein Center for Computational Neuroscience Tübingen (DE)
- National Cancer Institute (US)
- Hertie Institute for Clinical Brain Research (DE)
- Center for Cancer Research (US)
- Amsterdam University Medical Centers (NL)
- Neurological Surgery (US)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
- University of Tübingen (DE)
- Penn State Milton S. Hershey Medical Center (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- JAMA Oncology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1001/jamaoncol.2025.0329
- Citations
- 10
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 13.54