Plasma endostatin at intensive care admission is independently associated with acute kidney injury, dialysis, and mortality in COVID-19
Endostatin at ICU admission was independently associated with AKI, RRT, and 90-day mortality in ICU patients with COVID-19. In addition, endostatin improved the prediction of AKI and 90-day mortality, highlighting its potential as a biomarker for early risk stratification in intensive care.
Authors
- Hans Friberg (ORCID: https://orcid.org/0000-0002-5588-0098)
- Hazem Koozi (ORCID: https://orcid.org/0000-0002-5892-3524)
- Anders Larsson (ORCID: https://orcid.org/0000-0002-0702-8343)
- Martin Spångfors (ORCID: https://orcid.org/0000-0001-8754-899X)
- Ingrid Didriksson (ORCID: https://orcid.org/0000-0003-1334-7583)
- Attila Frigyesi (ORCID: https://orcid.org/0000-0002-0155-4828)
- Jonas Engström (ORCID: https://orcid.org/0000-0003-1421-3640)
- Ahmad Zwawi
Institutions
- Uppsala University (SE)
- Uppsala University Hospital (SE)
- Lund University (SE)
- Kristianstad University (SE)
- Skåne University Hospital (SE)
Publication Details
- Journal
- Intensive Care Medicine Experimental
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1186/s40635-025-00748-6
- Citations
- 2
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Crafoordska Stiftelsen
- Lunds Universitet
- Hjärt-Lungfonden
- Centralsjukhuset Kristianstad
- Skånes universitetssjukhus
- Hans-Gabriel och Alice Trolle-Wachtmeisters stiftelse för medicinsk forskning