Infection risk in atopic dermatitis patients treated with biologics and <scp>JAK</scp> inhibitors: <scp>BioDay</scp> results

This cohort study demonstrated an increased risk of infection during JAKi treatment compared to dupilumab for moderate-to-severe AD. These findings enhance understanding of the differential infection risk with targeted therapies in AD, aiding tailored treatment choices that consider patient-specific risks such as prior skin infections.

Authors

Institutions

Publication Details

Journal
Journal of the European Academy of Dermatology and Venereology
Published
2025-04-03
DOI
https://doi.org/10.1111/jdv.20674
Citations
16
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
32.08

Funders

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article

Infection risk in atopic dermatitis patients treated with biologics and JAK inhibitors: BioDay results

Celeste M. Boesjes, Marijke Kamsteeg, Simone Stadhouders‐Keet, Marjolein S. de Bruin-Weller et al.
16 citations
Journal of the European Academy of Dermatology and Venereology
Dermatology and Skin Diseases
32.08
article

Infection risk in atopic dermatitis patients treated with biologics and JAK inhibitors: BioDay results

Celeste M. Boesjes, Marijke Kamsteeg, Simone Stadhouders‐Keet, Marjolein S. de Bruin-Weller, Klaziena Politiek, Francine C. van Erp, Laura Loman, Anneke M. T. van Lynden‐van Nes, Wouter R. H. Touwslager, Lian F. van der Gang, Marlies de Graaf, Annebeth Flinterman, Nicolaas P. A. Zuithoff, Berit Velstra, Antoni Gostyński, Inge Marjet Haeck, Marie L. A. Schuttelaar, Shiarra M. Stewart, Albert J. Oosting, Wianda A. Christoffers, Octavian I. Bacoș‐Cosma, Lisette Berntsen‐Zandbergen, Keneshka Atash
article en
16 citations

Abstract

This cohort study demonstrated an increased risk of infection during JAKi treatment compared to dupilumab for moderate-to-severe AD. These findings enhance understanding of the differential infection risk with targeted therapies in AD, aiding tailored treatment choices that consider patient-specific risks such as prior skin infections.

Journal of the European Academy of Dermatology and VenereologyVol. 39(12)
University Medical Center Groningen (NL), Radboud University Nijmegen (NL), Utrecht University (NL), Catharina Ziekenhuis (NL), Medisch Centrum Leeuwarden (NL), Radboud University Medical Center (NL), University Medical Center Utrecht (NL), Reinier de Graaf Hospital (NL), Spaarne Ziekenhuis (NL), St. Antonius Ziekenhuis (NL), Diakonessenhuis hospital (NL), IJsselland Ziekenhuis (NL), Haga Hospital (NL), Isala (NL), Tergooi (NL), Meander Medisch Centrum (NL), Spaarne Gasthuis (NL)
Eli Lilly and Company, Pfizer, Sanofi, Regeneron Pharmaceuticals, LEO Pharma
Good health and well-being
Openalex Percentile: Top 0%
Dermatology and Skin Diseases
32.08
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