Evidence of Stem Cell Entrapment in <scp>AN69</scp> Membranes During Continuous Renal Replacement Therapy
Allo-HSCT can be performed successfully in pediatric patients with severe septic shock requiring CRRT, offering a potentially life-saving option in urgent transplant situations. This case highlights that although HSPCs can be entrapped on AN69 membranes, engraftment was not compromised. Our findings provide novel insights into HSPC interactions with AN69 membranes during CRRT, and further studies are needed to quantify stem cell loss and explore its clinical implications.
Authors
- Selman Kesici (ORCID: https://orcid.org/0000-0003-4746-6986)
- Benan Bayrakçı (ORCID: https://orcid.org/0000-0003-3307-0948)
- Izzet Turkalp Akbasli (ORCID: https://orcid.org/0000-0003-3055-7355)
- Fatma Visal Okur (ORCID: https://orcid.org/0000-0002-1679-6205)
- Şafak Güçer (ORCID: https://orcid.org/0000-0002-6021-4612)
- Ozlem Saritas Nakib
Institutions
- Cleveland Clinic (US)
- Children’s Institute (US)
- Birmingham Children's Hospital (GB)
- Hacettepe University (TR)
Publication Details
- Journal
- Artificial Organs
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1111/aor.15004
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gazi Üniversitesi
- Hacettepe Üniversitesi