Restoration of Miro1’s N-terminal GTPase function alleviates prenatal stress-induced mitochondrial fission via Drp1 modulation
Prenatal glucocorticoid-mediated Miro1 downregulation contributes to dysfunction in mitochondrial dynamics through Drp1 phosphorylation (Ser616) in differentiating neurons.
Authors
- Jae Ryong Lim
- Jee Hyeon Yoon (ORCID: https://orcid.org/0009-0001-1704-1779)
- Young Hyun Jung (ORCID: https://orcid.org/0000-0002-2308-6308)
- Gee Euhn Choi (ORCID: https://orcid.org/0000-0003-2725-6826)
- Ji Hyeon Cho
- Chang Woo Chae (ORCID: https://orcid.org/0000-0002-3556-3546)
- Mo Ran Park
- Ho Jae Han (ORCID: https://orcid.org/0000-0002-0657-1766)
- Ji Yong Park
Institutions
- Seoul National University (KR)
- Chungnam National University (KR)
- Soonchunhyang University (KR)
- Jeju National University (KR)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1186/s12964-025-02172-5
- Citations
- 2
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Research Foundation of Korea