Long‐Term Monitoring of Patients With Persistent Atrial Fibrillation After Pulsed Field Ablation
Most studies have followed patients with persistent atrial fibrillation (PeAF) using 12-lead or 24-h Holter electrocardiography, but this may overestimate the effectiveness of pulsed field ablation (PFA) in the treatment of PeAF. This study aimed to investigate the feasibility of PFA in patients with PeAF and follow-up using insertable cardiac monitoring that can provide information on the actual status of atrial arrhythmia (AA) recurrence after PFA. We prospectively enrolled 49 patients with PeAF who underwent PFA strategy comprising superior vena cava isolation, pulmonary vein isolation, and posterior wall box isolation between December 2022 and January 2024. After median follow-up of 14.1 months, 30 patients (61.22%) had zero AA burden. Kaplan-Meier analysis show that the freedom from recurrence increased with arrhythmia duration thresholds, from 59.54% to 80.50% (duration < 2 min vs. duration > 48 h, p = 0.040). Safety events occurred in two patients (one transient ischemic attack and one pseudoaneurysm). PFA is an effective modality for the treatment of patients with PeAF.
Authors
- Ying Cao (ORCID: https://orcid.org/0000-0003-4593-0319)
- Aobo Gong (ORCID: https://orcid.org/0000-0002-6655-6357)
- Rongzheng Yue
- Min Xu (ORCID: https://orcid.org/0000-0002-6638-1454)
- Xianjin Hu (ORCID: https://orcid.org/0000-0003-4827-218X)
- Xuechuan Dan
- Hongde Hu (ORCID: https://orcid.org/0000-0003-3878-6136)
- Dayong Zhang (ORCID: https://orcid.org/0000-0003-1537-1704)
- Wentao Li (ORCID: https://orcid.org/0000-0003-3868-413X)
- Ziru Li (ORCID: https://orcid.org/0000-0002-2755-9299)
- Yao Tong (ORCID: https://orcid.org/0009-0003-5605-5078)
- Wenzhai Cao
- Fanghui Li (ORCID: https://orcid.org/0000-0001-6580-3726)
- Kui Li (ORCID: https://orcid.org/0000-0002-5684-3918)
- Rui Zeng (ORCID: https://orcid.org/0000-0001-8164-9183)
- Hua Fu (ORCID: https://orcid.org/0000-0002-1105-9644)
- Kaijun Cui
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Sichuan Mianyang 404 Hospital (CN)
- Zigong First People's Hospital (CN)
- Second People’s Hospital of Yibin (CN)
Publication Details
- Journal
- Pacing and Clinical Electrophysiology
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1111/pace.15185
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jiangsu Development and Reform Commission
- Sichuan University
- Health Commission of Sichuan Province
- West China Hospital, Sichuan University