<scp>Cyp51A</scp> Dysfunction Leads to Higher Susceptibility to Azoles Including Fluconazole in <i>Aspergillus fumigatus</i>
It was suggested that FLCZ can inhibit Cyp51B rather than Cyp51A and that this unequal inhibition leads to higher azole susceptibility of the two isolates harbouring Cyp51A dysfunction.
Authors
- Akira Watanabe (ORCID: https://orcid.org/0000-0002-3057-2937)
- Hidetaka Majima (ORCID: https://orcid.org/0000-0001-9988-021X)
- Katsuhiko Kamei (ORCID: https://orcid.org/0000-0002-6067-9049)
- Naoto Maruguchi
- Teppei Arai (ORCID: https://orcid.org/0000-0002-2798-5829)
Institutions
- Chiba University Hospital (JP)
- Chiba Hospital (JP)
Publication Details
- Journal
- Mycoses
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/myc.70052
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- Chiba University
- Japan Society for the Promotion of Science