Mismatch Repair Status and Lymph Node Ratio in Survival Prediction of Stage <scp>II</scp>/<scp>III</scp> Rectal Cancer Patients: A Comprehensive Analysis of a Multi‐Center Retrospective Study
Integrating LNR based on the microsatellite status of colorectal tumors provides comprehensive prognostic predictions, enhancing postoperative prognostic considerations for tumor patients. Additionally, our study suggests that patients with stage II and III colorectal cancer with dMMR status do not require any adjuvant chemotherapy postoperatively.
Authors
- Chunze Zhang (ORCID: https://orcid.org/0000-0002-2063-5631)
- Weizheng Liang (ORCID: https://orcid.org/0000-0001-9244-6875)
- Weifeng Gao
- Wenwen Pang (ORCID: https://orcid.org/0000-0002-3892-8707)
- Kailong Zhao (ORCID: https://orcid.org/0009-0005-5173-5749)
- Xinyu Liu (ORCID: https://orcid.org/0000-0002-5180-6958)
- Kemin Ni (ORCID: https://orcid.org/0000-0002-7415-5393)
- Xipeng Zhang (ORCID: https://orcid.org/0009-0007-6259-1589)
- Xueliang Wu
- Zhiquan Tan
- Xiaomin Su (ORCID: https://orcid.org/0000-0003-0943-7156)
- Jun Xue
Institutions
- Hebei North University (CN)
- Nankai University (CN)
- Tianjin First Center Hospital (CN)
- Tianjin People's Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/cam4.70756
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Tianjin City