Osteoclastogenesis in Patients With Systemic Sclerosis With and Without Calcinosis Cutis

Calcinosis in patients with SSc is associated with an increased propensity of peripheral blood cells to form osteoclasts. Targeted inhibition of osteoclastogenesis may provide a specific therapeutic option for patients with SSc-associated calcinosis.

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Publication Details

Journal
ACR Open Rheumatology
Published
2025-04-01
DOI
https://doi.org/10.1002/acr2.70029
Citations
2
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
2.94

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article

Osteoclastogenesis in Patients With Systemic Sclerosis With and Without Calcinosis Cutis

Leland W.K. Chung, Arturo Borzutzky, Felipe Sánchez Barría, Antonia Valenzuela et al.
2 citations
ACR Open Rheumatology
Systemic Sclerosis and Related Diseases
2.94
article

Osteoclastogenesis in Patients With Systemic Sclerosis With and Without Calcinosis Cutis

Leland W.K. Chung, Arturo Borzutzky, Felipe Sánchez Barría, Antonia Valenzuela, Guillermo J. Pérez, Carolina Iturriaga, Rebeca Montalva
article en
2 citations

Abstract

Calcinosis in patients with SSc is associated with an increased propensity of peripheral blood cells to form osteoclasts. Targeted inhibition of osteoclastogenesis may provide a specific therapeutic option for patients with SSc-associated calcinosis.

ACR Open RheumatologyVol. 7(4)
Pontificia Universidad Católica de Chile (CL), Stanford University (US)
Agencia Nacional de Investigación y Desarrollo
Good health and well-being
Openalex Percentile: Top 11%
Systemic Sclerosis and Related Diseases
2.94
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