Efficacy of 0.05% cyclosporine A on tear inflammatory cytokines and goblet cell function after corneal refractive surgery

For patients undergoing refractive surgery, the application of 0.05% CsA suppressed the expression of inflammatory cytokines such as IFN-γ and TNF-α, and preserved goblet cell function. These effects ultimately contribute to maintaining ocular surface stability and alleviating dry eye related symptoms during the early postoperative period following refractive surgery.

Authors

Institutions

Publication Details

Journal
Journal of Ophthalmic Inflammation and Infection
Published
2025-04-03
DOI
https://doi.org/10.1186/s12348-025-00462-0
Citations
2
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
3.76

Funders

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article

Efficacy of 0.05% cyclosporine A on tear inflammatory cytokines and goblet cell function after corneal refractive surgery

Min Li, Ning Chen, Xin Liu, Yuying Liu et al.
2 citations
Journal of Ophthalmic Inflammation and Infection
Ocular Surface and Contact Lens
3.76
article

Efficacy of 0.05% cyclosporine A on tear inflammatory cytokines and goblet cell function after corneal refractive surgery

Min Li, Ning Chen, Xin Liu, Yuying Liu, Ting Zhao, Wenzhe Qian, Bilian Ke, Yue Wu
article en
2 citations

Abstract

For patients undergoing refractive surgery, the application of 0.05% CsA suppressed the expression of inflammatory cytokines such as IFN-γ and TNF-α, and preserved goblet cell function. These effects ultimately contribute to maintaining ocular surface stability and alleviating dry eye related symptoms during the early postoperative period following refractive surgery.

Journal of Ophthalmic Inflammation and InfectionVol. 15(1)
Shanghai Jiao Tong University (CN), Renji Hospital (CN), Shanghai First People's Hospital (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 8%
Ocular Surface and Contact Lens
3.76
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Efficacy of 0.05% cyclosporine A on tear inflammatory cytokines and goblet cell function after corneal refractive surgery — Min Li, Ning Chen, et al. · Journal of Ophthalmic Inflammation and Infection (2025) | TGRS Research Map | TGRS