Cell-type-specific subtyping of epigenomes improves prognostic stratification of cancer
In summary, cell-type-specific combinatorial clustering is a valuable strategy to help dissect and improve current prognostic classifications of cancer in terms of the underlying cell-type-specific epigenetic and transcriptomic alterations.
Authors
- Qi Luo (ORCID: https://orcid.org/0000-0001-9000-4133)
- Andrew E. Teschendorff (ORCID: https://orcid.org/0000-0001-7410-6527)
Institutions
- Shanghai Institute of Nutrition and Health (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Genome Medicine
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1186/s13073-025-01453-5
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Science Foundation
- National Natural Science Foundation of China