Modelling the impact of microbiome on immunotherapy efficacy in metastatic melanoma patients

Background: The gut microbiota has garnered interest as a predictor of the effects of immunotherapies in cancer patients. Previous studies have identified specific fecal taxa and metabolites linked to positive treatment outcomes in patients with unresectable cutaneous melanoma undergoing targeted or immunotherapy. Our study aims to investigate the gut microbiome's potential as a predictor of immunotherapy response in metastatic melanoma patients.

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Publication Details

Journal
EJC Skin Cancer
Published
2025-01-01
DOI
https://doi.org/10.1016/j.ejcskn.2025.100490
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Modelling the impact of microbiome on immunotherapy efficacy in metastatic melanoma patients

Míriam Potrony, Teresa Torres, Cristina Carrera, J. Mateu et al.
EJC Skin Cancer
Cancer Immunotherapy and Biomarkers
article

Modelling the impact of microbiome on immunotherapy efficacy in metastatic melanoma patients

Míriam Potrony, Teresa Torres, Cristina Carrera, J. Mateu, Judit Companys, Pedro Iglesias, Josep Malvehy, N. Calbet, Susana Puig
article en

Abstract

Background: The gut microbiota has garnered interest as a predictor of the effects of immunotherapies in cancer patients. Previous studies have identified specific fecal taxa and metabolites linked to positive treatment outcomes in patients with unresectable cutaneous melanoma undergoing targeted or immunotherapy. Our study aims to investigate the gut microbiome's potential as a predictor of immunotherapy response in metastatic melanoma patients.

EJC Skin CancerVol. 3
Instituto de Salud Carlos III (ES), Hospital Clínic de Barcelona (ES), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES), Universitat de Barcelona (ES)
Openalex Percentile: Top 90%
Cancer Immunotherapy and Biomarkers
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Modelling the impact of microbiome on immunotherapy efficacy in metastatic melanoma patients — Míriam Potrony, Teresa Torres, et al. · EJC Skin Cancer (2025) | TGRS Research Map | TGRS