Evaluation of the cagA, dupA, sabA, babA, and iceA1 Gene Expressions in H. pylori Strains Isolated from Patients with Gastric Cancer and Peptic Ulcer Disease
Our finding shows that the expressions of <i>cagA, dupA</i>, and <i>babA</i> virulence genes in <i>H. pylori</i> strains isolated from gastric biopsies of both GC and PUD patients are significantly higher than the NUD ones. Therefore, screening and treating the infection caused by this bacterium and determining the genotype in patients may prevent the progression of the disease.
Authors
- Mohsen Zargar (ORCID: https://orcid.org/0000-0002-3108-5655)
- Razieh Nazari (ORCID: https://orcid.org/0000-0003-4819-5735)
- Roohollah Fateh (ORCID: https://orcid.org/0000-0002-2073-5552)
- Ahmad Hormati (ORCID: https://orcid.org/0000-0002-1322-1318)
- Maryam Kianmehr
Institutions
- Shariati Hospital (IR)
- Qom Islamic Azad University (IR)
- Qom University of Medical Science and Health Services (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Anti-Cancer Agents in Medicinal Chemistry
- Published
- 2025-04-03
- DOI
- https://doi.org/10.2174/0118715206350551250319065557
- Citations
- 1
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 2.01