The osteoinductive and osseointegration properties of decellularized extracellular matrix bone derived from different sites
Our data indicated that the xenogenic dECM scaffolds in MCB position possess the most significant biocompatibility and in vitro and in vivo induced osteogenesis and osseointegration properties. This study provides a more complete basis for the selection of dECM scaffolds in bone defect repair. In future studies of dECM composites applied to bone tissue engineering (BTE), utilizing the middle part of cancellous bone may be the best solution.
Authors
- Weikang Xu (ORCID: https://orcid.org/0000-0001-6351-3944)
- Wei‐Hua Huang (ORCID: https://orcid.org/0000-0001-8951-075X)
- Huinan Yin
- Xiayu Cai
- Lijing Hao (ORCID: https://orcid.org/0000-0003-2710-5112)
- Chujie Xiao
Institutions
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Guangdong Academy of Sciences (CN)
- South China University of Technology (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Bone and Joint Research
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1302/2046-3758.144.bjr-2024-0080.r3
- Citations
- 4
- Primary Topic
- Tissue Engineering and Regenerative Medicine
- Type
- article
- Field-Weighted Citation Impact
- 8.03
Funders
- National Natural Science Foundation of China
- Guangzhou Municipal Science and Technology Project