Metastasis of Small Cell Lung Cancer to the External Auditory Canal: A Case Report

Patients with lung cancer often develop distant metastases; however, metastasis to the external auditory canal is rare. We report the case of a 77-year-old man who presented with left-sided hearing loss, otalgia, and a red mass in the left external auditory canal. Computed tomography revealed masses in the left external auditory canal, lung, and pancreas. Histopathological analysis confirmed small cell lung cancer, with thyroid transcription factor 1 positivity in multiple lesions, suggesting a primary tumor in lung. Treatment with carboplatin and etoposide led to a reduction in metastatic lesions, including those in the external auditory canal, and improved hearing impairment. This case highlights a rare instance in which chemotherapy improved ear symptoms in a patient with small cell lung cancer metastasis to the external auditory. Written informed consent was obtained from the patient for the publication of this case report and accompanying images.

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Publication Details

Journal
Thoracic Cancer
Published
2025-04-01
DOI
https://doi.org/10.1111/1759-7714.70059
Primary Topic
Ear and Head Tumors
Type
article
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0.00
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article

Metastasis of Small Cell Lung Cancer to the External Auditory Canal: A Case Report

Atsushi Fujiwara, Toshiyuki Ito, Hajime Fujimoto, Tetsu Kobayashi et al.
Thoracic Cancer
Ear and Head Tumors
article

Metastasis of Small Cell Lung Cancer to the External Auditory Canal: A Case Report

Atsushi Fujiwara, Toshiyuki Ito, Hajime Fujimoto, Tetsu Kobayashi, Shuji Kodama, Hiroto Miki, Hiroki Goto, Masamichi Yoshida
article en

Abstract

Patients with lung cancer often develop distant metastases; however, metastasis to the external auditory canal is rare. We report the case of a 77-year-old man who presented with left-sided hearing loss, otalgia, and a red mass in the left external auditory canal. Computed tomography revealed masses in the left external auditory canal, lung, and pancreas. Histopathological analysis confirmed small cell lung cancer, with thyroid transcription factor 1 positivity in multiple lesions, suggesting a primary tumor in lung. Treatment with carboplatin and etoposide led to a reduction in metastatic lesions, including those in the external auditory canal, and improved hearing impairment. This case highlights a rare instance in which chemotherapy improved ear symptoms in a patient with small cell lung cancer metastasis to the external auditory. Written informed consent was obtained from the patient for the publication of this case report and accompanying images.

Thoracic CancerVol. 16(7)
Mie University (JP), Mie Chuo Medical Center (JP)
Good health and well-being
Openalex Percentile: Top 90%
Ear and Head Tumors
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Metastasis of Small Cell Lung Cancer to the External Auditory Canal: A Case Report — Atsushi Fujiwara, Toshiyuki Ito, et al. · Thoracic Cancer (2025) | TGRS Research Map | TGRS