Immune Checkpoint inhibition in Mucosal Melanoma - A single centre retrospective analysis

Background: Since the introduction of immune checkpoint inhibition (ICI), the outcome of advanced cutaneous melanoma (CM) has improved substantially. Yet, for mucosal melanoma (MM), the prognosis in advanced settings remains dire, with reported median progression-free survival (mPFS) and median overall survival (mOS) of 4 months and 19 months, respectively (1). Prospective data from randomized clinical trials remain scarce due to the rarity of this melanoma subtype, highlighting the importance of retrospective real-world data.

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Publication Details

Journal
EJC Skin Cancer
Published
2025-01-01
DOI
https://doi.org/10.1016/j.ejcskn.2025.100537
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
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article

Immune Checkpoint inhibition in Mucosal Melanoma - A single centre retrospective analysis

Teresa Amaral, L. Flatz, U. Leiter-Stöppke, Katharina Frey et al.
EJC Skin Cancer
Cancer Immunotherapy and Biomarkers
article

Immune Checkpoint inhibition in Mucosal Melanoma - A single centre retrospective analysis

Teresa Amaral, L. Flatz, U. Leiter-Stöppke, Katharina Frey, Andreas Meiwes, M. Nyhuus Bendix Rasch, Lena Nanz
article en

Abstract

Background: Since the introduction of immune checkpoint inhibition (ICI), the outcome of advanced cutaneous melanoma (CM) has improved substantially. Yet, for mucosal melanoma (MM), the prognosis in advanced settings remains dire, with reported median progression-free survival (mPFS) and median overall survival (mOS) of 4 months and 19 months, respectively (1). Prospective data from randomized clinical trials remain scarce due to the rarity of this melanoma subtype, highlighting the importance of retrospective real-world data.

EJC Skin CancerVol. 3
Kantonsspital St. Gallen (CH), Guided Therapeutics (United States) (US), University of Tübingen (DE)
Zero hunger
Openalex Percentile: Top 90%
Cancer Immunotherapy and Biomarkers
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