Mesh Fixation with Cyanoacrylate Glue vs. Conventional Sutures in Inguinal Hernias

Background: Inguinal hernia repair is one of the most common surgical procedures. While conventional sutures are widely used for mesh fixation, they can lead to increased postoperative pain and complications. Cyanoacrylate glue has emerged as a potential alternative for non-traumatic fixation. Objective: To compare the outcomes of mesh fixation using N-Hexyl cyanoacrylate glue versus conventional sutures in inguinal hernia repair. Methods: A prospective randomized comparative study was conducted with 100 patients divided into two groups: Group A (Glue) and Group B (Sutures). Parameters such as operation time, postoperative pain (VAS score), seroma formation, surgical site infection (SSI), hospital stay, and recurrence rates were evaluated. Results: The mean procedure time was significantly lower in the Glue group (65.86 ± 7.75 minutes) compared to the Sutures group (81.12 ± 9.50 minutes; p < 0.0001). Postoperative pain (VAS scores) was lower in the Glue group on days 3, 5, and 8. Seroma and SSI rates were reduced in the Glue group. Recurrence rates at 6 months were also lower for the Glue group (0%) compared to Sutures (6%; p = 0.04). Conclusion: Cyanoacrylate glue is a safe and effective alternative for mesh fixation in inguinal hernia repair, offering reduced operation time, pain, and complications.