Quantitative Systems Pharmacology (QSP) Analysis of Medicinal Mechanisms for Heart and Kidney Function Enhancement, and Optimal Dosage Strategies for Odronextamab in B-NHL Patients

This study investigates the mechanisms of medications impacting heart and kidney function and optimizes dosing strategies for Odronextamab. Utilizing secondary source data and a comprehensive Quantitative systems pharmacology (QSP), the research unveils hidden salt loss mechanisms, explores medication impacts on cardiovascular health, and recommends a personalized dosing regimen for Odronextamab. Validation against real-world data ensures the model's accuracy. Clinical implications emphasize the model's role in understanding drug safety and efficacy, providing guidance for B-NHL patients.