Neutrophil rate in patients treated with cemiplimab: the search for a new biomarker

Background: Immunotherapy has revolutionized cancer therapy. Checkpoint inhibitors have demonstrated unprecedented rates of durable responses in some of the most difficult-to-treat cancers; however, many treated patients do not respond. There is a growing need to identify biomarkers that will improve the selection of patients who will best respond to therapy, further elucidate drug mechanisms of action, and help tailor therapy regimens.

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Publication Details

Journal
EJC Skin Cancer
Published
2025-01-01
DOI
https://doi.org/10.1016/j.ejcskn.2025.100708
Primary Topic
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Type
article
Field-Weighted Citation Impact
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article

Neutrophil rate in patients treated with cemiplimab: the search for a new biomarker

Laura Eibenschutz, Giulia Spallone, Cosimo Di Raimondo, Pasquale Frascione et al.
EJC Skin Cancer
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
article

Neutrophil rate in patients treated with cemiplimab: the search for a new biomarker

Laura Eibenschutz, Giulia Spallone, Cosimo Di Raimondo, Pasquale Frascione, Francesca Sperati
article en

Abstract

Background: Immunotherapy has revolutionized cancer therapy. Checkpoint inhibitors have demonstrated unprecedented rates of durable responses in some of the most difficult-to-treat cancers; however, many treated patients do not respond. There is a growing need to identify biomarkers that will improve the selection of patients who will best respond to therapy, further elucidate drug mechanisms of action, and help tailor therapy regimens.

EJC Skin CancerVol. 3
University of Rome Tor Vergata (IT), San Gallicano Hospital (IT)
Zero hunger
Openalex Percentile: Top 93%
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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