Analysis of the Longitudinal Behavior of Serum Levels of Soluble Flt1 and Placental Growth Factor in Pregnant Patients With Systemic Lupus Erythematosus
Pregnant patients with SLE who developed PE had higher sFlt1 levels and sFlt1:PlGF ratios and lower PlGF levels, and these last two changes were detected at the beginning of second trimester, before clinical manifestation. SLE activity did not interfere with longitudinal behavior of these angiogenic markers.
Authors
- Evandro Mendes Klumb (ORCID: https://orcid.org/0000-0001-9546-3144)
- Guilherme Ramires de Jesús (ORCID: https://orcid.org/0000-0002-6715-0180)
- Flávia Cunha dos Santos (ORCID: https://orcid.org/0000-0002-6304-5797)
- Luís Cristóvão Pôrto (ORCID: https://orcid.org/0000-0003-1499-1821)
- Evandro Silva Freire Coutinho (ORCID: https://orcid.org/0000-0002-4649-7353)
- Jeane de Souza Nogueira (ORCID: https://orcid.org/0000-0002-4952-2278)
- Nilson Ramires de Jesús (ORCID: https://orcid.org/0000-0003-2890-1110)
- Marcela Ignacchiti Lacerda (ORCID: https://orcid.org/0000-0002-7311-5496)
Institutions
- Universidade do Estado do Rio de Janeiro (BR)
Publication Details
- Journal
- Arthritis Care & Research
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1002/acr.25536
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00