Efficacy and safety of nivolumab in the treatment of non-trichoblastic adnexal carcinoma

Background: Adnexal carcinomas are rare skin cancers. In the case of non-resectable cancer, there is no consensus on management. Treatment options most often include radiotherapy and/or different chemotherapy protocols. The efficacy of anti PD1 agents has been suggested in trichoblastic carcinomas, but remains to be demonstrated in adnexal carcinomas in general.

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Publication Details

Journal
EJC Skin Cancer
Published
2025-01-01
DOI
https://doi.org/10.1016/j.ejcskn.2025.100677
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
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article

Efficacy and safety of nivolumab in the treatment of non-trichoblastic adnexal carcinoma

Aude Fléchon, M. Beylot‐Barry, L. Mortier, M. Boileau et al.
EJC Skin Cancer
Cancer and Skin Lesions
article

Efficacy and safety of nivolumab in the treatment of non-trichoblastic adnexal carcinoma

Aude Fléchon, M. Beylot‐Barry, L. Mortier, M. Boileau, Assia Lamrani-Ghaouti, C. Lebbé, A. Marabelle, Thomas Jouary, Sylvie Chevret, Maxime Batistella, François Goldwasser, Olivier Bouché, Clotilde Simon, P. Saiag, Esma Saada Bouzid, Y. Kazbennaou
article en

Abstract

Background: Adnexal carcinomas are rare skin cancers. In the case of non-resectable cancer, there is no consensus on management. Treatment options most often include radiotherapy and/or different chemotherapy protocols. The efficacy of anti PD1 agents has been suggested in trichoblastic carcinomas, but remains to be demonstrated in adnexal carcinomas in general.

EJC Skin CancerVol. 3
Inserm (FR), Institut Gustave Roussy (FR), Centre Hospitalier Universitaire de Bordeaux (FR), Centre Hospitalier Universitaire de Lille (FR), CHU Ambroise Paré (BE), Lille’s Cardiology Hospital (FR), Hôpital Cochin (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre Hospitalier De Pau (FR), Centre Léon Bérard (FR), Centre Hospitalier Universitaire de Reims (FR), Hôpital Ambroise-Paré (FR), UniCancer Group (FR), Hôpital Saint-Louis (FR), Centre Antoine Lacassagne (FR), Clinique Ambroise Paré (FR), Onco Lille (FR), Bicêtre Hospital (FR), Carrier (United States) (US), Université de Reims Champagne-Ardenne (FR)
Good health and well-being
Openalex Percentile: Top 87%
Cancer and Skin Lesions
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