Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis

Redo-bilateral lung transplant in previous heart-lung transplant is a rare operation. We describe our surgical and medical management experience with a heart-lung transplant recipient who developed chronic lung allograft dysfunction and invasive <i>Scedosporium</i> apiospermum infection. The patient underwent a redo-bilateral lung transplant followed by a combination of inhaled voriconazole, caspofungin, and olorofim for a prolonged period. We observed no issues with bronchial anastomosis healing, and the patient is doing well on 1-year follow-up. This report outlines a successful management approach to this rare complication of heart-lung transplant recipients.

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Publication Details

Journal
JHLT Open
Published
2025-04-03
DOI
https://doi.org/10.1016/j.jhlto.2025.100247
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Field-Weighted Citation Impact
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article

Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis

Sahar A. Saddoughi, Anja C. Roden, Philip J. Spencer, Nischal Ranganath et al.
JHLT Open
Transplantation: Methods and Outcomes
article

Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis

Sahar A. Saddoughi, Anja C. Roden, Philip J. Spencer, Nischal Ranganath, Paschalis Vergidis, Mauricio A. Villavicencio, James G. Scott, Akshay Chauhan, Richard C. Daly
article en

Abstract

Redo-bilateral lung transplant in previous heart-lung transplant is a rare operation. We describe our surgical and medical management experience with a heart-lung transplant recipient who developed chronic lung allograft dysfunction and invasive <i>Scedosporium</i> apiospermum infection. The patient underwent a redo-bilateral lung transplant followed by a combination of inhaled voriconazole, caspofungin, and olorofim for a prolonged period. We observed no issues with bronchial anastomosis healing, and the patient is doing well on 1-year follow-up. This report outlines a successful management approach to this rare complication of heart-lung transplant recipients.

JHLT OpenVol. 8
Mayo Clinic (US), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US)
Openalex Percentile: Top 88%
Transplantation: Methods and Outcomes
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Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis — Sahar A. Saddoughi, Anja C. Roden, et al. · JHLT Open (2025) | TGRS Research Map | TGRS