Popliteal artery adventitial disease: A case report and understanding the pathophysiology and management

<h2>Abstract</h2> Popliteal artery adventitial disease (PAAD) underlies a significant portion of vascular conditions of the lower extremities, often culminating in critical limb ischemia and warranting a greater clinical understanding for effective management. Characterized by the cystic degeneration of the adventitia of the popliteal artery, PAAD remains a challenging condition both in terms of diagnosis and treatment. This review seeks to explore the complex pathophysiology, diagnostic criteria, and current management strategies, as well as discussing emerging therapies and future outlook for patients with PAAD.

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Publication Details

Journal
JVS-Vascular Insights
Published
2025-01-01
DOI
https://doi.org/10.1016/j.jvsvi.2025.100221
Primary Topic
Muscle and Compartmental Disorders
Type
article
Field-Weighted Citation Impact
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article

Popliteal artery adventitial disease: A case report and understanding the pathophysiology and management

Hideaki Obara, Lewis J. Levien, Paresh Mistry, Rakesh Agarwal
JVS-Vascular Insights
Muscle and Compartmental Disorders
article

Popliteal artery adventitial disease: A case report and understanding the pathophysiology and management

Hideaki Obara, Lewis J. Levien, Paresh Mistry, Rakesh Agarwal
article en

Abstract

<h2>Abstract</h2> Popliteal artery adventitial disease (PAAD) underlies a significant portion of vascular conditions of the lower extremities, often culminating in critical limb ischemia and warranting a greater clinical understanding for effective management. Characterized by the cystic degeneration of the adventitia of the popliteal artery, PAAD remains a challenging condition both in terms of diagnosis and treatment. This review seeks to explore the complex pathophysiology, diagnostic criteria, and current management strategies, as well as discussing emerging therapies and future outlook for patients with PAAD.

JVS-Vascular InsightsVol. 3
University of the Witwatersrand (ZA), Keio University (JP), CARE Hospitals (IN), Wits University Donald Gordon Medical Centre (ZA)
Zero hunger
Openalex Percentile: Top 88%
Muscle and Compartmental Disorders
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Popliteal artery adventitial disease: A case report and understanding the pathophysiology and management — Hideaki Obara, Lewis J. Levien, et al. · JVS-Vascular Insights (2025) | TGRS Research Map | TGRS