Airway mucus and <sup>129</sup>Xe MRI ventilation after single inhaler triple therapy in asthma
In participants with GINA4-5 asthma, who had been poorly controlled on ICS/LABA, single-inhaler FF/UMEC/VI resulted in improved VDP and FEV<sub>1</sub> at 6-weeks. These improvements persisted 1-year later when airway markers were also significantly improved, consistent with the reversal of airway remodelling.
Authors
- Hana Serajeddini (ORCID: https://orcid.org/0000-0003-1977-6979)
- Anurag Bhalla (ORCID: https://orcid.org/0000-0003-0613-0546)
- H.K. Kooner (ORCID: https://orcid.org/0000-0003-4040-4977)
- Narinder Paul (ORCID: https://orcid.org/0000-0002-1102-0125)
- Marrissa J. McIntosh (ORCID: https://orcid.org/0000-0003-2678-458X)
- Grace Párraga (ORCID: https://orcid.org/0000-0002-5619-4145)
- Cory Yamashita (ORCID: https://orcid.org/0000-0003-2040-4996)
- Sam Tcherner (ORCID: https://orcid.org/0000-0001-8728-0428)
- Ali Mozaffaripour (ORCID: https://orcid.org/0009-0008-0497-9830)
- M.C. Sherwood
- Eveline Durom
Institutions
- Western University (CA)
- Health First (US)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1183/23120541.01333-2024
- Citations
- 3
- Primary Topic
- Atomic and Subatomic Physics Research
- Type
- article
- Field-Weighted Citation Impact
- 3.74
Funders
- GlaxoSmithKline