Well-differentiated primary pleural liposarcoma

Primary pleural liposarcoma is a rare, slow-growing tumor, representing < 10% of pleural tumors, originating from residual remains of primitive mesenchymal tissue.We present the case of a 61-year-old male patient with chest pain and rapidly progressive dyspnea, observing in the imaging studies a hypodense tumor in the left hemithorax with Hounsfield units of -30 to -130 fatty tissue range with dimensions of 29.5 16.1 21.9 cm.Excision surgery together with chemotherapy and radiotherapy is the therapeutic alternative that has reported the greatest benefit in these patients.