Human Schwann Cell-Derived Extracellular Vesicle Isolation, Bioactivity Assessment, and Omics Characterization
The study establishes a robust framework for SCEV isolation and their comprehensive characterization, which is consistent with their therapeutic potential in neurological applications. This work provides a valuable proteomic, lipidomic, and miRNA dataset to inform future advancements in applying SCEV to the experimental treatment of neurological injuries and diseases.
Authors
- W. Dalton Dietrich (ORCID: https://orcid.org/0000-0002-8732-4942)
- Yee‐Shuan Lee (ORCID: https://orcid.org/0000-0003-0250-6542)
- James D. Guest (ORCID: https://orcid.org/0000-0003-0931-0286)
- Aisha Khan (ORCID: https://orcid.org/0000-0001-7409-9208)
- Risset Silvera
- Damien Daniel Pearse (ORCID: https://orcid.org/0000-0003-1783-221X)
- Allan D. Levi (ORCID: https://orcid.org/0000-0002-0713-8497)
- Hassan Al‐Ali (ORCID: https://orcid.org/0000-0002-8899-3443)
- Pascal J. Goldschmidt‐Clermont (ORCID: https://orcid.org/0000-0003-2915-0101)
- Indigo P Williams
- Júlia Teixeira Oliveira (ORCID: https://orcid.org/0000-0002-3471-9369)
- Yelena Pressman
- Adriana E Nettina
Institutions
- University of Miami (US)
- Neurological Surgery (US)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/ijn.s500159
- Citations
- 9
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 7.25