Neutrophil Extracellular Traps Capturing SARS-CoV-2 in the Lung Tissue (Alveoli and Parenchyma) Cause Microthrombi ― A Strategy to Eliminate SARS-CoV-2 From the Circulation as Degraded Fibrin Clots ―

This novel theory suggests that NETosis and microthrombosis are phenomena inevitably elicited in COVID-19, and in combination they are a system newly termed "NETombosis". Undegraded fibrin clots remaining in the microcirculation may be the cause of the sequelae, because they cause long-lasting circulatory failure in various organs.

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Publication Details

Journal
Circulation Reports
Published
2025-04-03
DOI
https://doi.org/10.1253/circrep.cr-24-0157
Primary Topic
Tracheal and airway disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Neutrophil Extracellular Traps Capturing SARS-CoV-2 in the Lung Tissue (Alveoli and Parenchyma) Cause Microthrombi ― A Strategy to Eliminate SARS-CoV-2 From the Circulation as Degraded Fibrin Clots ―

Hiroshi Katayama
Circulation Reports
Tracheal and airway disorders
article

Neutrophil Extracellular Traps Capturing SARS-CoV-2 in the Lung Tissue (Alveoli and Parenchyma) Cause Microthrombi ― A Strategy to Eliminate SARS-CoV-2 From the Circulation as Degraded Fibrin Clots ―

Hiroshi Katayama
article en

Abstract

This novel theory suggests that NETosis and microthrombosis are phenomena inevitably elicited in COVID-19, and in combination they are a system newly termed "NETombosis". Undegraded fibrin clots remaining in the microcirculation may be the cause of the sequelae, because they cause long-lasting circulatory failure in various organs.

Circulation ReportsVol. 7(5)
Okayama Psychiatric Medical Center (JP)
Openalex Percentile: Top 90%
Tracheal and airway disorders
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