Regulation of microtubule nucleation in glioblastoma cells by ARF GTPase-activating proteins GIT1 and GIT2 and protein kinase C

We propose that GIT2 phosphorylation provides a novel regulatory mechanism for microtubule nucleation in glioblastoma cells, contributing to their invasive properties.

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Publication Details

Journal
Cancer Cell International
Published
2025-04-02
DOI
https://doi.org/10.1186/s12935-025-03740-y
Primary Topic
Microtubule and mitosis dynamics
Type
article
Field-Weighted Citation Impact
0.00

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article

Regulation of microtubule nucleation in glioblastoma cells by ARF GTPase-activating proteins GIT1 and GIT2 and protein kinase C

Pavel Dráber, Omar Skalli, Vladimíra Sládková, Tetyana Sulimenko et al.
Cancer Cell International
Microtubule and mitosis dynamics
article

Regulation of microtubule nucleation in glioblastoma cells by ARF GTPase-activating proteins GIT1 and GIT2 and protein kinase C

Pavel Dráber, Omar Skalli, Vladimíra Sládková, Tetyana Sulimenko, Vadym Sulimenko, Eduarda Dráberová, Věra Vosecká
article en

Abstract

We propose that GIT2 phosphorylation provides a novel regulatory mechanism for microtubule nucleation in glioblastoma cells, contributing to their invasive properties.

Cancer Cell InternationalVol. 25(1)
Cytoskeleton (United States) (US), University of Memphis (US)
University of Memphis, Ministerstvo Školství, Mládeže a Tělovýchovy, Masarykova Univerzita, Lékařská fakulta, Masarykova univerzita
Openalex Percentile: Top 93%
Microtubule and mitosis dynamics
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