CSF outflow from the human spinal canal: preliminary results from an anatomical specimen-based model
The described model makes it possible to examine CSF outflow routes from the human spinal subarachnoid space. The methodology is reproducible, feasible, and does not require specialized equipment. Preliminary results have revealed two potential CSF outflow pathways that have been previously observed in animal models: along the spinal nerves and to the epidural tissue and vessels.
Authors
- Sylwia Tarka (ORCID: https://orcid.org/0000-0003-1271-8418)
- Radosław Rzepliński (ORCID: https://orcid.org/0000-0002-1112-6261)
- Bogdan Ciszek (ORCID: https://orcid.org/0000-0002-0740-5049)
- Steven T. Proulx (ORCID: https://orcid.org/0000-0003-2154-8502)
- Tomasz Stępień (ORCID: https://orcid.org/0000-0003-2831-1321)
Institutions
- University of Bern (CH)
- Medical University of Warsaw (PL)
- Children's Memorial Health Institute (PL)
- Institute of Psychiatry and Neurology (PL)
Publication Details
- Journal
- Fluids and Barriers of the CNS
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1186/s12987-025-00645-w
- Citations
- 8
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 7.27
Funders
- Fundacja na rzecz Nauki Polskiej
- Warszawski Uniwersytet Medyczny
- Uniwersytet Warszawski