Cannabimimetic and discriminative stimulus effects of hexahydrocannabinols in mice
9(R)-HHC is likely to possess abuse liability in humans, whereas 9(S)-HHC may produce weak Δ<sup>9</sup>-THC-like psychoactivity in humans. The differences in the pharmacology between the two HHC epimers may lead to a range of effects in human users depending on the ratio of the epimers consumed.
Authors
- Cassandra Prioleau
- Luli R. Akinfiresoye
- Julie A. Marusich (ORCID: https://orcid.org/0000-0002-0203-4867)
Institutions
- United States Department of Justice (US)
- Drug Enforcement Administration (US)
- RTI International (US)
Publication Details
- Journal
- Journal of Psychopharmacology
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1177/02698811251330739
- Citations
- 1
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- United States Drug Enforcement Administration