Sarcoma of the Uterus. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/074, June 2024)

<b>Purpose</b> This is an official, recently updated guideline published and coordinated by the German Society of Gynecology and Obstetrics ( <i>Deutsche Gesellschaft für Gynäkologie und Geburtshilfe</i> , DGGG) together with the Austrian Society of Gynecology and Obstetrics ( <i>Österreichische Gesellschaft für Gynäkologie und Geburtshilfe</i> , OEGGG) and the Swiss Society of Gynecology and Obstetrics ( <i>Schweizerische Gesellschaft für Gynäkologie und Geburtshilfe</i> , SGGG) as part of the guidelines program. Because of their rarity and heterogeneous histopathology, uterine sarcomas are challenging in terms of their clinical management, and treatment requires a multidisciplinary approach. <b>Methods</b> This S2k guideline was first published in 2015. The update published here is again the result of a structured consensus of a representative interdisciplinary group of mandate holders and experts who carried out a selective search of the literature on uterine sarcomas. Members of the participating professional societies achieved a formal consensus on recommendations and statements after a structured consensus process. <b>Recommendations</b> Recommendations were made about the epidemiology, classification, staging of uterine sarcomas, symptoms, general diagnostic workup, general pathology and genetic predisposition for uterine sarcomas, leiomyosarcomas, endometrial stromal sarcomas (low-grade and high-grade), undifferentiated uterine sarcomas, adenosarcomas, and rhabdomyosarcoma of the uterus in children and adolescents. The guideline also discusses the follow-up of uterine sarcomas, the management of morcellated uterine sarcomas, and the information provided to patients.

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Publication Details

Journal
Geburtshilfe und Frauenheilkunde
Published
2025-04-01
DOI
https://doi.org/10.1055/a-2496-2591
Primary Topic
Uterine Myomas and Treatments
Type
article
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article

Sarcoma of the Uterus. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/074, June 2024)

Thomas J. Vogl, Karin Kast, Clemens Tempfer, U. Ulrich et al.
Geburtshilfe und Frauenheilkunde
Uterine Myomas and Treatments
article

Sarcoma of the Uterus. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/074, June 2024)

Thomas J. Vogl, Karin Kast, Clemens Tempfer, U. Ulrich, Florian Heitz, Dominik Denschlag, Ingolf Juhasz‐Böss, Markus Wallwiener, Simone Hettmer, Dirk Vordermark, Peter Reichardt, Paul Gaß, Lars‐Christian Horn, Markus Follmann, Marco Johannes Battista, W. Cremer, Thomas Kröncke, Katja Lindel, Günter Köhler, Philipp Harter, Mathias K. Fehr, Gerlinde Egerer, Alexander Mustea, Heidemarie Haase, Edgar Petru, Jan Novotný, Eike-Christian Burandt, Falk C. Thiel, Hans‐Georg Strauß, Kerstin Rhiem
article en

Abstract

<b>Purpose</b> This is an official, recently updated guideline published and coordinated by the German Society of Gynecology and Obstetrics ( <i>Deutsche Gesellschaft für Gynäkologie und Geburtshilfe</i> , DGGG) together with the Austrian Society of Gynecology and Obstetrics ( <i>Österreichische Gesellschaft für Gynäkologie und Geburtshilfe</i> , OEGGG) and the Swiss Society of Gynecology and Obstetrics ( <i>Schweizerische Gesellschaft für Gynäkologie und Geburtshilfe</i> , SGGG) as part of the guidelines program. Because of their rarity and heterogeneous histopathology, uterine sarcomas are challenging in terms of their clinical management, and treatment requires a multidisciplinary approach. <b>Methods</b> This S2k guideline was first published in 2015. The update published here is again the result of a structured consensus of a representative interdisciplinary group of mandate holders and experts who carried out a selective search of the literature on uterine sarcomas. Members of the participating professional societies achieved a formal consensus on recommendations and statements after a structured consensus process. <b>Recommendations</b> Recommendations were made about the epidemiology, classification, staging of uterine sarcomas, symptoms, general diagnostic workup, general pathology and genetic predisposition for uterine sarcomas, leiomyosarcomas, endometrial stromal sarcomas (low-grade and high-grade), undifferentiated uterine sarcomas, adenosarcomas, and rhabdomyosarcoma of the uterus in children and adolescents. The guideline also discusses the follow-up of uterine sarcomas, the management of morcellated uterine sarcomas, and the information provided to patients.

Geburtshilfe und FrauenheilkundeVol. 85(04)
Goethe University Frankfurt (DE), Universität Hamburg (DE), Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Johannes Gutenberg University Mainz (DE), Medical University of Graz (AT), Heidelberg University (DE), Universitätsmedizin Greifswald (DE), University Hospital Bonn (DE), University Medical Center Freiburg (DE), University Hospital Augsburg (DE), University Hospital Heidelberg (DE), Klinik für Frauenheilkunde (DE), Städtisches Klinikum Karlsruhe (DE), University Medical Center of the Johannes Gutenberg University Mainz (DE), Accadis Hochschule Bad Homburg (DE), Martin-Luther-Krankenhaus (DE), Alb Fils Kliniken (DE), German Cancer Society (DE), Universitätsklinik für Frauenheilkunde und Geburtshilfe (AT), University Medical Center Hamburg-Eppendorf (DE), Universitäts Frauenklinik (DE), University Hospital Leipzig (DE), University Hospital Frankfurt (DE), Kliniken Essen-Mitte (DE), Comprehensive Cancer Center Erlangen (DE), University Hospital in Halle (DE), University Hospital Cologne (DE), Helios Hospital Berlin-Buch (DE), Klinikum Chemnitz (DE), Chirurgische Universitätsklinik Heidelberg (DE), Kantonsspital Frauenfeld (CH), Martin Luther University Halle-Wittenberg (DE), Charité - Universitätsmedizin Berlin (DE), Ruhr University Bochum (DE)
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Uterine Myomas and Treatments
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