Identification and Cross-Platform Validation of Sparse Molecular Classifiers for Antibody-Mediated and T-Cell–Mediated Rejection After Kidney Transplantation
Rigid variable selection strategies can yield sparse molecular classifiers for allograft rejection phenotypes with preserved accuracy and prognostic value across different molecular diagnostic platforms, which may facilitate their interpretation and clinical implementation.
Authors
- Pierre Marquet (ORCID: https://orcid.org/0000-0001-7698-0760)
- Dennis A. Hesselink (ORCID: https://orcid.org/0000-0003-1871-1962)
- Henriëtte de Loor (ORCID: https://orcid.org/0000-0003-4421-6340)
- Haralampos Hatzikirou (ORCID: https://orcid.org/0000-0002-1270-7885)
- Ben Sprangers (ORCID: https://orcid.org/0000-0003-1314-9675)
- Wilfried Gwinner (ORCID: https://orcid.org/0000-0003-1703-893X)
- Maarten Naesens (ORCID: https://orcid.org/0000-0002-5625-0792)
- Jasper Callemeyn (ORCID: https://orcid.org/0000-0003-2235-9842)
- Marian C. Clahsen‐van Groningen (ORCID: https://orcid.org/0000-0003-0565-9560)
- Dany Anglicheau (ORCID: https://orcid.org/0000-0001-5793-6174)
- Candice Roufosse (ORCID: https://orcid.org/0000-0002-6490-4290)
- Dirk Kuypers (ORCID: https://orcid.org/0000-0001-5546-9680)
- Iacopo Cristoferi (ORCID: https://orcid.org/0000-0002-4282-9103)
- Evelyne Lerut (ORCID: https://orcid.org/0000-0003-3937-7190)
- Priyanka Koshy (ORCID: https://orcid.org/0000-0002-2313-5122)
- Robert C. Minnee (ORCID: https://orcid.org/0000-0002-9494-3717)
- Philip F. Halloran (ORCID: https://orcid.org/0000-0003-1371-1947)
- Josué Manik Nava-Sedeño (ORCID: https://orcid.org/0000-0001-9451-8676)
- Jan Hinrich Bräsen (ORCID: https://orcid.org/0000-0002-2863-3067)
- Andreas Deutsch (ORCID: https://orcid.org/0000-0002-9005-6897)
- Jack Beadle (ORCID: https://orcid.org/0000-0002-5399-7209)
- Amaryllis H. Van Craenenbroeck (ORCID: https://orcid.org/0000-0003-4728-9406)
- Marie Essig (ORCID: https://orcid.org/0000-0002-2030-5616)
Institutions
- Hôpital Necker-Enfants Malades (FR)
- Imperial College Healthcare NHS Trust (GB)
- University of Alberta (CA)
- Inserm (FR)
- Khalifa University of Science and Technology (AE)
- Université Paris Cité (FR)
- Rega Institute for Medical Research (BE)
- Erasmus MC (NL)
- Medizinische Hochschule Hannover (DE)
- Institut Necker Enfants Malades (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- North West London Pathology (GB)
- Helmholtz Centre for Infection Research (DE)
- Hôpital Ambroise-Paré (FR)
- Erasmus MC Cancer Institute (NL)
- Centre for Inflammation Research (GB)
- Université de Limoges (FR)
- Technische Universität Dresden (DE)
- RWTH Aachen University (DE)
- Universidad Nacional Autónoma de México (MX)
- Erasmus University Rotterdam (NL)
- KU Leuven (BE)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1016/j.ekir.2025.03.048
- Citations
- 1
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.99