Time-restricted feeding reduced blood pressure and improved cardiac structure and function by regulating both circulating and local renin-angiotensin systems in spontaneously hypertensive rat model
TRF effectively inhibits RAS activity in both circulating and LV tissues, thereby lowering BP and mitigating structural and functional cardiac damage associated with hypertension.
Authors
- Chongshuang Yang (ORCID: https://orcid.org/0000-0003-3621-4548)
- Razif Abas (ORCID: https://orcid.org/0000-0003-0309-6573)
- Raja Abdul Wafy Raja Muhammad Rooshdi
- Weijing Sun (ORCID: https://orcid.org/0000-0001-6549-9605)
- Ummi Nadira Daut (ORCID: https://orcid.org/0000-0001-8991-9520)
- Canzhang Liu
- Teng Gao
- Jie Yan (ORCID: https://orcid.org/0000-0003-4413-8610)
- Xin Yi (ORCID: https://orcid.org/0000-0002-9737-8901)
Institutions
- Universiti Putra Malaysia (MY)
- North China University of Science and Technology Affiliated Hospital (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1371/journal.pone.0321078
- Citations
- 4
- Primary Topic
- Dietary Effects on Health
- Type
- article
- Field-Weighted Citation Impact
- 4.66