Taletrectinib in <i>ROS1</i> + Non–Small Cell Lung Cancer: TRUST

Taletrectinib showed a high response rate with durable responses, robust IC activity, prolonged PFS, favorable safety, and low rates of neurologic adverse events in TKI-naïve and pretreated patients.

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Publication Details

Journal
Journal of Clinical Oncology
Published
2025-04-03
DOI
https://doi.org/10.1200/jco-25-00275
Citations
30
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
45.55
Controls
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article

Taletrectinib in ROS1 + Non–Small Cell Lung Cancer: TRUST

Nathan A. Pennell, Huijie Fan, Filippo de Braud, Rose Lai et al.
30 citations
Journal of Clinical Oncology
Lung Cancer Treatments and Mutations
45.55
article

Taletrectinib in ROS1 + Non–Small Cell Lung Cancer: TRUST

Nathan A. Pennell, Huijie Fan, Filippo de Braud, Rose Lai, Caicun Zhou, Lyudmila Bazhenova, Shuanglian Li, M. Pérol, Misako Nagasaka, Fei-Wu Ran, Enriqueta Felip, Yuichiro Ohe, Wenfeng Chen, Geoffrey Liu, Yongchang Zhang, Wei Li, Xianyu Zhang, Xicheng Wang, Anwen Xiong
article en
30 citations

Abstract

Taletrectinib showed a high response rate with durable responses, robust IC activity, prolonged PFS, favorable safety, and low rates of neurologic adverse events in TKI-naïve and pretreated patients.

Journal of Clinical OncologyVol. 43(16)
Tongji University (CN), Cleveland Clinic (US), Central South University (CN), University of Toronto (CA), University of Milan (IT), Guangdong Pharmaceutical University (CN), University of California, Irvine (US), Princess Margaret Cancer Centre (CA), University of California San Diego (US), Hunan Cancer Hospital (CN), Centre de Recherche en Cancérologie de Lyon (FR), Shanghai Pulmonary Hospital (CN), Vall d'Hebron Hospital Universitari (ES), Shanghai East Hospital (CN), Tokyo National Hospital (JP), First Affiliated Hospital of Zhengzhou University (CN)
Good health and well-being
Openalex Percentile: Top 0%
Lung Cancer Treatments and Mutations
45.55
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