Evaluating the antimicrobial and anti-inflammatory mechanisms of dexmedetomidine in managing bone infection: a laboratory perspective
DXMT at 5 µM is an optimal dose to reduce infection-induced cellular stress and promote bone healing in osteomyelitis in vitro, balancing antimicrobial effects and cytotoxicity.
Authors
- Günseli Çubukçuoğlu Deniz (ORCID: https://orcid.org/0000-0002-2407-2450)
- Erkan Tuncay (ORCID: https://orcid.org/0000-0002-6675-2534)
- Evrim Güneş Altuntaş (ORCID: https://orcid.org/0000-0003-4897-9388)
- Duru Aras‐Tosun (ORCID: https://orcid.org/0000-0001-8236-4315)
- M. Kocaoglu (ORCID: https://orcid.org/0000-0002-2259-0131)
Institutions
- Ankara University (TR)
Publication Details
- Journal
- BMC Musculoskeletal Disorders
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1186/s12891-025-08555-6
- Citations
- 1
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01