USP15-modified ADMSCs-Exo alleviates chondrocyte damage and effectively relieved osteoarthritis by inducing M2 polarization of macrophages through deubiquitinating FOXC1
USP15-modified ADMSC-derived Exos facilitated M2 polarization of macrophages and improved chondrocyte injury by deubiquitination of FOXC1.
Authors
- Qinghe Ding
- Qingfeng Liang (ORCID: https://orcid.org/0000-0003-0000-3167)
- Liang Zhao (ORCID: https://orcid.org/0000-0002-9479-0562)
- Jingchao Tan
- Wei Niu (ORCID: https://orcid.org/0000-0002-0894-5696)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Twelfth Guangzhou City People's Hospital (CN)
- Guangzhou Psychiatric Hospital (CN)
- 421 Hospital of PLA (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1186/s13018-025-05742-y
- Citations
- 4
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 3.22