Sleep disturbances, shift work, and epigenetic ageing in working-age adults: findings from the Young Finns study
Among various sleep measures, symptoms of obstructive sleep apnoea appear to be most consistently associated with accelerated epigenetic ageing even after adjusting for various health-related and socioeconomic factors. Shift work seems to have a crucial role in the relationship between sleep disturbances and epigenetic ageing in working-age adults.
Authors
- Aino Saarinen (ORCID: https://orcid.org/0000-0003-4495-8360)
- Saara Marttila (ORCID: https://orcid.org/0000-0003-3071-3784)
- Nina Mononen (ORCID: https://orcid.org/0000-0002-7482-9159)
- Mika A. P. Kähönen (ORCID: https://orcid.org/0000-0002-4510-7341)
- Emma Raitoharju (ORCID: https://orcid.org/0000-0002-7023-8706)
- Pashupati P. Mishra (ORCID: https://orcid.org/0000-0001-5177-3431)
- Terho J. Lehtimäki (ORCID: https://orcid.org/0000-0002-2555-4427)
- Ilkka Autio
- Liisa Keltikangas–Järvinen
- Olli T. Raitakari
Institutions
- University of Helsinki (FI)
- Tampere University of Applied Sciences (FI)
- University of Turku (FI)
- Tampere University (FI)
- Helsinki Institute of Physics (FI)
- Turku University Hospital (FI)
- Tampere University Hospital (FI)
- Tampere University (FI)
- Fimlab (Finland) (FI)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1186/s13148-025-01860-w
- Citations
- 4
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 8.47
Funders
- Helsingin Yliopisto
- Academy of Finland