External Evaluation of Population Pharmacokinetic Models of Ustekinumab in Patients with Inflammatory Bowel Disease

The models developed by Xu et al and Adedokun et al exhibited the most promising predictive performance and potential clinical applicability for model-informed precision dosing. Refinements to these models and further research are required to enhance their use in personalized UST therapies for IBD.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2025-04-03
DOI
https://doi.org/10.1097/ftd.0000000000001329
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

External Evaluation of Population Pharmacokinetic Models of Ustekinumab in Patients with Inflammatory Bowel Disease

Carles Iniesta Navalón, Lorena Rentero‐Redondo, Elena Urbieta‐Sanz, Manuel Ríos Saorín et al.
Therapeutic Drug Monitoring
Inflammatory Bowel Disease
article

External Evaluation of Population Pharmacokinetic Models of Ustekinumab in Patients with Inflammatory Bowel Disease

Carles Iniesta Navalón, Lorena Rentero‐Redondo, Elena Urbieta‐Sanz, Manuel Ríos Saorín, Juan Manuel Neira-Torrecillas, Irene Garcia-Masegosa, José Gil-Almela
article en

Abstract

The models developed by Xu et al and Adedokun et al exhibited the most promising predictive performance and potential clinical applicability for model-informed precision dosing. Refinements to these models and further research are required to enhance their use in personalized UST therapies for IBD.

Therapeutic Drug MonitoringVol. 47(6)
American Pharmacists Association (US), Hospital Universitario Reina Sofía (ES), Hospital Reina Sofía de Murcia (ES), Universidad de Murcia (ES)
Good health and well-being
Openalex Percentile: Top 92%
Inflammatory Bowel Disease
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