Hydrogen-bonded organic framework for regulating pathogenic autoantigen and oxidative stress in psoriasis treatment
This study develops a cobalt porphyrin-based hydrogen-bonded organic framework (Co-HOF) to scavenge reactive oxygen species (ROS) and target the pathogenic peptide LL-37, thereby disrupting psoriasis progression.
Authors
- Rong Cao (ORCID: https://orcid.org/0000-0002-2398-399X)
- Qiuxia Li (ORCID: https://orcid.org/0000-0001-5835-0749)
- Hui Yuan (ORCID: https://orcid.org/0000-0002-4935-3988)
- Y. Frank Cheng (ORCID: https://orcid.org/0000-0002-3379-1828)
- Tian‐Fu Liu (ORCID: https://orcid.org/0000-0001-9096-6981)
- Qi Yin (ORCID: https://orcid.org/0000-0001-5067-2372)
- Yuhang Li (ORCID: https://orcid.org/0000-0002-4443-3591)
- Jinlin Li
- Can‐Zhong Lu (ORCID: https://orcid.org/0000-0002-8298-4132)
Institutions
- Fujian Normal University (CN)
- Chinese Academy of Sciences (CN)
- Xiamen Institute of Rare-earth Materials (CN)
- Fujian Institute of Research on the Structure of Matter (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- National Science Review
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1093/nsr/nwaf132
- Citations
- 4
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 3.74