Ventricular Entry During Glioblastoma Resection is Associated With Reduced Survival and Increased Risk of Distant Recurrence
Our data suggest that VE during GBM resection is a significant independent risk factor for decreased survival and increased distant recurrence/LMD. While maximizing tumor resection remains critical, neurosurgeons must consider the potential adverse outcomes associated with VE because it may diminish the survival benefits of gross-total resection. Prospective studies are warranted to better understand the risks and benefits of VE in GBM surgery.
Authors
- Jeremy N. Rich (ORCID: https://orcid.org/0000-0001-7845-5302)
- Arka N. Mallela (ORCID: https://orcid.org/0000-0003-0993-198X)
- Megan Mantica (ORCID: https://orcid.org/0000-0002-6107-6696)
- Pascal Olivier Zinn (ORCID: https://orcid.org/0000-0003-0091-5887)
- Kalil G. Abdullah (ORCID: https://orcid.org/0000-0002-5662-0829)
- Jan Drappatz (ORCID: https://orcid.org/0000-0001-8187-7119)
- Neslihan Nisa Gecici
- Ahmed Habib (ORCID: https://orcid.org/0000-0003-4908-6987)
Institutions
- UPMC Hillman Cancer Center (US)
- University of Pittsburgh Medical Center (US)
- Neurological Surgery (US)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1227/neu.0000000000003431
- Citations
- 5
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 8.13