Strategies to Promote Resiliency: A Randomized Embedded Multifactorial Adaptative Platform (REMAP) Clinical Trial to Study Interventions to Improve Recovery After Surgery in High-Risk Patients
Pretreatment with metformin did not improve postoperative outcomes in this REMAP trial, although trial enrollment was markedly limited by the COVID-19 pandemic and is underpowered.
Authors
- Brian S. Zuckerbraun (ORCID: https://orcid.org/0000-0002-5226-1857)
- Katherine M. Reitz (ORCID: https://orcid.org/0000-0002-9397-321X)
- Oscar C. Marroquin (ORCID: https://orcid.org/0000-0002-0909-0319)
- Timothy D. Girard (ORCID: https://orcid.org/0000-0002-9833-4871)
- Matthew D. Neal (ORCID: https://orcid.org/0000-0001-8931-6236)
- Ryan Zeh (ORCID: https://orcid.org/0000-0003-2746-289X)
- Stephen A. Esper (ORCID: https://orcid.org/0000-0003-4839-8030)
- Jason Kennedy (ORCID: https://orcid.org/0000-0001-7604-899X)
- Christopher W. Seymour (ORCID: https://orcid.org/0000-0001-8330-8489)
- Jennifer Holder-Murray
- Farah Khandwala
- Kert Viele (ORCID: https://orcid.org/0000-0003-1804-9497)
- Michelle A. Detry (ORCID: https://orcid.org/0000-0002-2794-1439)
- Melanie Quintana (ORCID: https://orcid.org/0000-0002-1763-2704)
- Barbara A. Methé (ORCID: https://orcid.org/0000-0001-8711-1448)
- Hasan Nassereldine (ORCID: https://orcid.org/0000-0003-2298-3098)
- Anne B. Newman (ORCID: https://orcid.org/0000-0002-0106-1150)
- Derek Angus (ORCID: https://orcid.org/0000-0002-7026-5181)
- Alison Morris
- Scott Berry
- Timothy R. Billiar
Institutions
- University of Pittsburgh (US)
- UPMC Health System (US)
- Berry & Associates (United States) (US)
- UPMC Presbyterian (US)
- VA Pittsburgh Healthcare System (US)
Publication Details
- Journal
- Annals of Surgery Open
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1097/as9.0000000000000566
- Citations
- 1
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 1.22