Associations of serum choline, betaine and trimethylamine N-oxide with gestational diabetes mellitus among Chinese pregnant women

Serum choline and betaine, but not TMAO, tend to be inversely associated with GDM odds among Han Chinese women with singleton gestation. Especially among those women with abnormal weight gain during pregnancy, higher serum betaine was associated with lower GDM likelihood.

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Publication Details

Journal
BMJ Nutrition Prevention & Health
Published
2025-04-03
DOI
https://doi.org/10.1136/bmjnph-2024-001111
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Associations of serum choline, betaine and trimethylamine N-oxide with gestational diabetes mellitus among Chinese pregnant women

Jie Zhu, Kefeng Yang, Cassandra Johnson, Guofeng Lou et al.
BMJ Nutrition Prevention & Health
Gestational Diabetes Research and Management
article

Associations of serum choline, betaine and trimethylamine N-oxide with gestational diabetes mellitus among Chinese pregnant women

Jie Zhu, Kefeng Yang, Cassandra Johnson, Guofeng Lou, Shiyin Wu, Meiqin Cai, Lingpeng Lu, Yuhong Liu, Jie Jia, Liang Wang, Xiaoxi Shen, Hui Wu, J Lauren Butler, G Saikia
article en

Abstract

Serum choline and betaine, but not TMAO, tend to be inversely associated with GDM odds among Han Chinese women with singleton gestation. Especially among those women with abnormal weight gain during pregnancy, higher serum betaine was associated with lower GDM likelihood.

BMJ Nutrition Prevention & HealthVol. 8(1)
University of North Florida (US), Texas State University (US), Shanghai Jiao Tong University (CN), XinHua Hospital (CN), Shanghai University of Traditional Chinese Medicine (CN), Shanghai Traditional Chinese Medicine Hospital (CN), Seventh People's Hospital of Shanghai (CN), Viva Biotech (China) (CN), Marshall Health (US), Marshall University (US)
National Natural Science Foundation of China, Shanghai University of Traditional Chinese Medicine
Openalex Percentile: Top 91%
Gestational Diabetes Research and Management
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Associations of serum choline, betaine and trimethylamine N-oxide with gestational diabetes mellitus among Chinese pregnant women — Jie Zhu, Kefeng Yang, et al. · BMJ Nutrition Prevention & Health (2025) | TGRS Research Map | TGRS