Faecalibacterium prausnitzii-derived outer membrane vesicles reprogram gut microbiota metabolism to alleviate Porcine Epidemic Diarrhea Virus infection
F.prausnitzii and its OMVs play a critical role in mitigating PEDV infections. These findings provide a promising strategy to ameliorate PEDV infection in piglets. Video Abstract.
Authors
- Tianming Niu (ORCID: https://orcid.org/0000-0002-0241-8430)
- Jun-Hong Xing
- Jianzhong Wang (ORCID: https://orcid.org/0000-0001-7353-5995)
- Yanlong Jiang (ORCID: https://orcid.org/0000-0001-5843-4301)
- Boshi Zou
- Xin Cao (ORCID: https://orcid.org/0000-0003-3459-7207)
- Haibin Huang (ORCID: https://orcid.org/0000-0002-8357-432X)
- Yu Sun (ORCID: https://orcid.org/0000-0002-6608-1347)
- Jingtao Hu
- Guilian Yang (ORCID: https://orcid.org/0000-0001-5224-1592)
- Chunwei Shi (ORCID: https://orcid.org/0000-0001-7774-0400)
- Meiying Bao
- Wentao Yang (ORCID: https://orcid.org/0000-0002-1686-6883)
- Kuipeng Gao
- DongXing Zhang
- Nan Wang (ORCID: https://orcid.org/0000-0002-4197-4245)
- Yingjie Wang (ORCID: https://orcid.org/0000-0003-0920-9305)
- Di Zhang (ORCID: https://orcid.org/0000-0002-0228-5244)
- Chunfeng Wang (ORCID: https://orcid.org/0000-0002-1195-0920)
- Minghan Li (ORCID: https://orcid.org/0000-0003-0904-5611)
- Shumin Zhang (ORCID: https://orcid.org/0000-0003-2777-3938)
- Weining Sun (ORCID: https://orcid.org/0000-0002-3395-7840)
- Jingjing Qiu (ORCID: https://orcid.org/0000-0001-8156-1210)
- Tong Yu
- ShuHui Fan
- Yan Zeng
Institutions
- Jilin Agricultural University (CN)
Publication Details
- Journal
- Microbiome
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1186/s40168-025-02078-x
- Citations
- 11
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 8.87
Funders
- National Natural Science Foundation of China