Hyperparathyroidism—Jaw Tumor Syndrome: A Rare Case Report and Literature Review

Prompt identification of Hyperparathyroidism-Jaw Tumor Syndrome (HPT-JT) is vital, particularly for those with a family history or unusual symptoms like progressive facial changes. By employing a thorough diagnostic strategy that includes biochemical tests, imaging, and genetic analysis, we can achieve early diagnosis and effective intervention. In this case, the patient displayed maxillofacial tumors, hypercalcemia, and increased parathyroid hormone levels. Imaging confirmed a parathyroid adenoma, while histopathology showed characteristics of brown tumors. Subtotal parathyroidectomy is the recommended treatment. Additionally, regular follow-ups every 6 months involving biochemical tests and imaging are crucial for ensuring the best patient outcomes.

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Publication Details

Journal
Clinical Case Reports
Published
2025-04-01
DOI
https://doi.org/10.1002/ccr3.70390
Citations
1
Primary Topic
Oral and gingival health research
Type
article
Field-Weighted Citation Impact
2.02
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article

Hyperparathyroidism—Jaw Tumor Syndrome: A Rare Case Report and Literature Review

Maria Nazish Memon, Nurhadi Ibrahim, Alaa Jlailati, Maisam Ali Rajput et al.
1 citations
Clinical Case Reports
Oral and gingival health research
2.02
article

Hyperparathyroidism—Jaw Tumor Syndrome: A Rare Case Report and Literature Review

Maria Nazish Memon, Nurhadi Ibrahim, Alaa Jlailati, Maisam Ali Rajput, Mahesh Kumar Meghwar, Farina Fatima Siddiqui, Aakash Rai Khatri, Muhammad Momin Khan
article en
1 citations

Abstract

Prompt identification of Hyperparathyroidism-Jaw Tumor Syndrome (HPT-JT) is vital, particularly for those with a family history or unusual symptoms like progressive facial changes. By employing a thorough diagnostic strategy that includes biochemical tests, imaging, and genetic analysis, we can achieve early diagnosis and effective intervention. In this case, the patient displayed maxillofacial tumors, hypercalcemia, and increased parathyroid hormone levels. Imaging confirmed a parathyroid adenoma, while histopathology showed characteristics of brown tumors. Subtotal parathyroidectomy is the recommended treatment. Additionally, regular follow-ups every 6 months involving biochemical tests and imaging are crucial for ensuring the best patient outcomes.

Clinical Case ReportsVol. 13(4)
Damascus University (SY)
Good health and well-being
Openalex Percentile: Top 13%
Oral and gingival health research
2.02
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